Planning for NaNoWriMo: Switching Points of View?

So, I am kicking around some ideas for NaNoWriMo this year, and I have a few solid ideas. One idea I have in particular is a comic pitch that never got off the ground, but I would love to develop into something publishable. In order to use this aprticular concept, I have to make a big decision up front--should I write the story in the first-person, third-person or both?

The way I had envisioned the comic is that it would feature the storylines of two characters that would start out separately, but would eventually converge into one. One of the storylines featured a character narrating in first-person, and the other was presented in third-person. The problem is that it's much easier to switch perspectives in a comic, due to the visual nature of the medium. If I maintain the "switching perspectives" model when turning this idea into a novel, I run the risk of confusing readers. I've read a lot of articles on this subject recently, and it seems that switching perspective is generally frowned upon.

So, I've got a big decision to make. Do I ditch the multiple-POV idea and just go with a third-person throughout? Or do I run the risk of confusing readers but maintain the original vision I had for the storyline?